What is a possible cause of blood in the sputum and urine in a patient with type 2 hypersensitivity reaction?

A type 2 hypersensitivity reaction involves the immune system producing antibodies against specific antigens, leading to tissue damage and inflammation. Goodpasture syndrome is a prime example of this type of hypersensitivity reaction. It is characterized by the production of antibodies against the basement membrane of the lungs and kidneys, which results in pulmonary hemorrhage and glomerulonephritis.

In this condition, patients often present with blood in the sputum due to lung involvement, where the alveolar-capillary membrane is damaged, causing leakage of red blood cells into the airways. Additionally, the renal involvement can lead to hematuria, or blood in the urine, as the glomeruli are affected.

Other conditions listed do not typically present with both hemoptysis (blood in the sputum) and hematuria (blood in the urine) as direct manifestations of type 2 hypersensitivity. For instance, Grave's disease is primarily related to hyperthyroidism due to autoantibodies stimulating the thyroid gland. Allergic rhinitis, while an immune-mediated condition, is more related to type 1 hypersensitivity reactions involving IgE. Systemic lupus erythematosus (SLE) involves multiple mechanisms that can include type 3 hypersensitivity